Anna Sophia's Universe ~ Formerly Toparanormal.org
I'm a Judaeo-Christian Mystic, natural psychic and sensitive empath born under the Libra sign that has been blogging since 2007 on Toparanormal.org but decided that it was time to move things over to Blogger.com instead since it's a great platform and free :)
Lurasidone (Latuda) and ziprasidone (Geodon) are both
atypical antipsychotic medications used to treat schizophrenia and
bipolar disorder.They are similar in efficacy, but lurasidone may be associated with less weight gain and somnolence:
Efficacy
In
a study of outpatients with schizophrenia, lurasidone and ziprasidone
had similar efficacy, with an early onset of improvement in PANSS total
score.
Weight gain
Lurasidone is associated with less weight gain than other antipsychotics.A study found that lurasidone was associated with less weight gain than quetiapine and olanzapine.
Somnolence
Lurasidone is associated with less somnolence than ziprasidone.
Side effects
Common side effects of ziprasidone include uncontrolled body movements, sleepiness, and nausea.
Lurasidone is also used to treat depressive episodes associated with bipolar I disorder.
Lurasidone (Latuda)
Ziprasidone (Geodon)
Conditions treated
Schizophrenia, depressive episodes associated with bipolar I disorder
Schizophrenia, bipolar I disorder
Administration
Once daily tablet
Typically twice daily tablet, or injection given into muscles by a healthcare provider
Common side effects
Sleepiness
Uncontrolled body movements, sleepiness, nausea
This is for informational purposes only. For medical advice or diagnosis, consult a professional. Generative AI is experimental.
Latuda
has an average rating of 6.3 out of 10 from a total of 844 ratings on
Drugs.com. 51% of reviewers reported a positive effect, while 30%
reported a negative effect. Ziprasidone has an average rating of 5.7 out
of 10 from a total of 479 ratings on Drugs.com.
I was on Olanzapine for about 3 years after I had experienced seizures in 2018. They started me at 10 mg but then I went down to the lowest dose of 2.5 mg. It was the worst because I felt like a zombie, was tired all the time, was constipated, felt physically ill since it lowered my white blood cells so messed with my immune system and gained about 20 lbs because it spiked my blood sugar and prolactin levels. Thank goodness I was working out that entire time so when I went for blood tests everything was normal but that didn't change the fact that I wasn't feeling myself. No one could tell I gained 20 lbs but I could. I gained it in all the right places fortunately in my chest and my butt mostly. Thankfully after switching to the lowest dose of Lurasidone 20 mg I'm back to myself now. I did notice that I am still a bit tired, I sweat more when I'm hot because hard to regulate my body temperature and it does still have a bit of an effect on my blood sugar too. I keep cool & drink more water when I'm hot and I watch what I eat which makes all the difference. I feel less tired too when I don't have as many carbs. It's a small price to pay to keep me from going mutant mind. I can't be out of balance like that. I get way too psychic and it's just too much!
Olanzapine (Zyprexa) is an atypical antipsychotic medication that’s FDA-approved to treat bipolar disorder and schizophrenia.
Some
of olanzapine’s most common side effects are drowsiness, constipation,
and dry mouth. Weight gain is also a frequent complaint.
More
serious side effects can also occur. If you notice symptoms like
movement problems or abnormal changes in mood or behavior, contact your
healthcare provider right away.
Fly View Productions/E+ via Getty Images
Throughout life, it’s important to seek treatment for you or a loved one’s mental health when it’s needed. Many health conditions, life events, and other stressors can all take a toll on our well-being, leading us to seek advice from health experts.
Self-care techniques, support groups, therapy,
and other non-medication-based interventions are preferred ways to
manage our symptoms when possible. They’re often free — or side effect
free — ways to make progress toward our health goals. But in many cases,
medication is a necessary way to improve the situation that’s
complicating our lives.
When it comes to treating health conditions like bipolar disorder, schizophrenia, or even chemotherapy-induced nausea and vomiting, olanzapine (Zyprexa) is a common resource. And while it’s a useful medication, it has several risks and side effects to be aware of. Read more like this
Explore these related articles, suggested for readers like you.
Olanzapine is a once-daily oral medication that’s FDA-approved to treat bipolar disorder and schizophrenia in people ages 13 and older. It’s a type of atypical antipsychotic that comes in several forms:
A tablet that dissolves on your tongue (Zyprexa Zydis)
A long-lasting injection that’s dosed every 2 to 4 weeks (Zyprexa Relprevv)
A combination pill that contains olanzapine and fluoxetine (Symbyax)
A combination pill that contains olanzapine and samidorphan (Lybalvi)
How does olanzapine work for schizophrenia and bipolar disorder?
As mentioned, olanzapine is an atypical antipsychotic, also known as a “second generation” antipsychotic.
The exact way olanzapine works to promote healthy thought and behavior changes isn’t proven. But it’s thought to do so by balancing dopamine and serotonin levels in your brain. Changes in these hormone levels are thought to play a key role in bipolar disorder and schizophrenia.
9 side effects of olanzapine (and when to seek help)
Many of olanzapine’s side effects
are mild and/or manageable, but others can be more severe. Some are
also life-threatening in certain situations, so some people should avoid
olanzapine altogether. For instance, older adults with dementia-related psychosis shouldn’t take olanzapine — it can cause severe brain-related side effects and a higher risk of death.
Otherwise,
if you or a loved one are new to olanzapine, it’s helpful to know what
to expect. This isn’t an exhaustive list, but here are nine key side
effects to keep in mind while taking oral olanzapine.
1. Feeling more or less sleepy than normal
There’s a chance that olanzapine may interfere with your sleep schedule. But the specific way it does so varies for everyone.
Drowsiness
(or sleepiness) is one of olanzapine’s most common side effects. This
can also have an affect on your mental alertness or judgment. But on the
other end of the spectrum, insomnia is another common side effect.
If
you feel tired after taking olanzapine, ask your healthcare provider
about taking olanzapine around bedtime. And if you think olanzapine is
contributing to a late night under the covers, ask them if it’s better
to take your daily dose soon after waking up. Drowsiness also appears to
be dose-related, so you could ask them if a lower olanzapine dose may
be better.
2. Constipation
Medications like olanzapine have anticholinergic properties, meaning they can have a “drying” effect throughout your body. Constipation is one possible outcome of this.
If you develop constipation from olanzapine, certain dietary changes can help. Try to drink more water or eat foods that are high in fiber, such as whole grains, fruits, and vegetables. When needed, several over-the-counter medications for constipation are also available to consider.
3. Dry mouth
Many medications can cause dry mouth, including olanzapine. This is likely due to its anticholinergic nature.
There
are many ways you can try to treat dry mouth on your own. Drinking more
water or improving salivation by sucking on ice chips, rinsing with
cold water, or chewing sugarless gum can all help. But you could also
ask your healthcare provider about saliva substitutes or possibly lowering your olanzapine dose, as dry mouth is more likely to happen with higher doses.
4. Headache or dizziness
Headache and dizziness
are also common side effects of olanzapine. If you experience them,
they should get better as your body gets used to the medication. But if
they don’t go away or get worse at any point, contact your healthcare
provider for guidance.
5. Weight gain (alongside higher cholesterol and blood sugar)
Olanzapine can cause metabolic changes, meaning it can worsen your blood sugar and cholesterol levels. It can also lead to a bigger appetite than normal. These can come together to contribute to weight gain.
This
can become problematic, so your healthcare provider will likely monitor
your blood sugar while you’re taking olanzapine, especially if you’re living with diabetes. They should also monitor your cholesterol levels and body weight over time.
Lifestyle
changes, like diet and exercise, can help combat this. But if these
changes become bothersome or severe, talk to your healthcare provider.
They may switch you to another medication.
6. High prolactin levels
In a complex way, olanzapine can raise prolactin levels. It does this by the way it impacts dopamine. Prolactin is a natural hormone that’s found in our bodies, but too much of it can lead to side effects.
Common side effects of too much prolactin include a lower sex drive, menstrual irregularities, and mood changes. Gynecomastia (male breast development), nipple discharge, and fertility problems are also possible.
Olanzapine’s
effect on prolactin doesn’t appear to get better the longer you take
olanzapine, so let your healthcare provider know if any of these
symptoms are affecting you. They could change your medication routine or
offer others ways to help manage these symptoms.
7. Movement problems
Olanzapine can impact your body movements. It most often leads to shakiness or inability to sit still, but more serious risks are also possible.
Although rare, olanzapine may cause tardive dyskinesia (TD). TD can cause uncontrollable muscle movements, mostly of the face and tongue. Neuroleptic malignant syndrome is also possible, and it can be life-threatening. It can cause rigid muscles, fever, and confusion.
If
you notice any signs of unusual body movements, let your healthcare
provider know as soon as you can. These symptoms can be hard to get rid
of — especially if left untreated — so they may tell you to stop taking
olanzapine. But if your symptoms feel severe, it’s better to seek
medical attention right away.
8. Behavioral changes
It’s
possible to experience changes in mood or behavior while taking
olanzapine. Some of this is intended — olanzapine aims to promote
positive behavioral changes by the way it works. But some of these
changes can be unintentional or negative.
It’s possible to experience new or worsening depression, especially within the first few months of starting olanzapine. Thoughts of suicide
have also been reported. If you develop any feelings like these, make
sure to contact your healthcare provider right away. You could also call 988 for immediate support.
9. Serious skin rashes
Although very rare, olanzapine can cause serious skin rashes. It’s been linked to a condition called drug reaction with eosinophilia and systemic symptoms
(DRESS). This typically starts as a rash, but it can cause fever and
swelling throughout your body. If left untreated, DRESS can lead to
organ damage and become fatal.
Because
of this, if you develop a fever with symptoms like a rash, facial
swelling, or swollen lymph nodes, seek medical help right away.
When should I contact my healthcare provider about side effects from olanzapine?
If
you notice any serious side effects — such as movement problems,
changes in mood or behavior, or substantial weight gain — make sure to
contact your healthcare provider. You should also contact them for any
other side effects that are bothersome or don’t go away.
However,
if your symptoms are accompanied by confusion, a high fever, facial
swelling, or anything that feels severe, it’s better to seek medical
attention as soon as you can.
The bottom line
Olanzapine
is a prescription medication that treats bipolar disorder and
schizophrenia. There are many side effects to keep in mind while taking
olanzapine. Common ones are drowsiness, dry mouth, and constipation. But
in many cases, there are different approaches to managing side effects.
It’s important to let your healthcare provider know about any
olanzapine side effects that you experience.
So disappointed Ancestry got rid of their breakdowns for Southern Italy for vague definition instead:"Stretching from Italy to Turkey & the Middle East,our Southern Italy & Eastern Mediterranean region has been the historic crossroads of Europe,the Middle East, and Asia." It has seen empires-Greeks,Persians,Romans, Ottomans-come&go over thousands of years. The region has shaped civilizations worldwide through diverse contributions, including aqueducts&roads, seafaring and trade,geometry,medical ethics,architecture,govt,art,philosophy,language&even cuisine.
Thank goodness I already have my break downs&my parents break downs too cause now u have to pay for it. I also uploaded my DNA to an ancient DNA site so I have even more! Actual matches from their samples. I have purchased only 5 levels but might purchase more when I get a job.
Seems ancient Jews were pushed out of Middle East and went to Italy, Spain & Portugal instead. My people in Calabria told to leave or convert by Catholic Church so some stayed&became crypto Jews. Now seems hiding DNA from my ppl too. It's an exclusive club! Strange to keep numbers down on purpose.
The Lost Tribes Of Israel are not really lost if you ask me! They were pushed out and excluded from the club. All of us are different and different sects. Not everyone worships the same. It's not fair to be pushed aside and treated differently cause we aren't as stern in our practices.
Pharisees took over imposed their rules&taxes on us ancient Jews so we left Israel and went to Italy, Portugal and Spain but oh no they couldn't stand that so they used their Roman Catholic Church they created to force some to leave/convert instead of letting us live as Jews of Moses!
I remember that one ancient Jewish people were being observed and they weren't good Jewish enough because they were said to only lite candles to worship. Why is that anyone's business how Jews practice as long as it's positive and not hurting anyone? It's not fair at all!
Pharisees/S.O.Satan fake clowns will do anything to keep all us real Jews apart. I'd be really surprised & impressed if the ancient Jews of the Tribes of Israel were recognized and included again. It's easy to find us! Already did DNA test with ancient DNA search but NOW DNA being purposely hidden! Satanists are not real anything! They are the most false and low vibe there are!! I know this world is a mess because they control EVERYTHING!!!
To say I'm proud to be part Israeli and Jew is an understatement! I am so thrilled you can't even imagine. I understand where my religious roots are now and it makes sense since I write about The Harmonious Order, Civilized Society and Circle Society.
My mother's mom's maiden name was Jewish Italian, Ferraro. The ancient DNA site I uploaded my DNA to matched my DNA to Tel Megiddo, Israel. Also, Calabria where both parents are from, is also known for were a lot of Jews used to live and they were even called The Jews Of Calabria! I read that over 50% of Calabrese have Jewish heritage.
I just wanted to add that I had another ancient dna match in Saifi, Lebanon Israel too.
Oct 23rd Update:
My ancient DNA breakdown. I was referring to Aramaean but I mistakenly said Armenian. So I am connected to Moses on his father's side. Arameans/Aramaeans,were a tribal Semitic people in the ancient Near East...often referred to as the land of Aram...modern Syria. pic.twitter.com/gZLEn8V1SY
— 🗽EarthAngel777✡️✝️♎️⚖️❤️🌈🌹🕊️🐍 (@Angel777Ea34727) October 23, 2024
Deuteronomy 26:5 Then you shall declare before the Lord your God: “My father was a wandering Aramean, and he went down into Egypt with a few people and lived there and became a great nation, powerful and numerous.
— 🗽EarthAngel777✡️✝️♎️⚖️❤️🌈🌹🕊️🐍 (@Angel777Ea34727) October 23, 2024
Also want to remind everyone that my parents are from Calabria as in The Jews Of Calabria! "legends state that Reggio Calabria was founded by Aschenez, a great grandchild of Noah. Italian Jews were the first Jews in the Diaspora, coming to Calabria in 167 BC during the time of the Macabbees."
"Physical activity can lower your blood glucose up to 24 hours or more after your workout by making your body more sensitive to insulin. Become familiar with how your blood glucose responds to exercise. Checking your blood glucose level more often before and after exercise can help you see the benefits of activity."
"Insulin sensitivity is increased, so your muscle cells are better able
to use any available insulin to take up glucose during and after
activity.
When your muscles contract during activity, your cells are able to take
up glucose and use it for energy whether insulin is available or not."
My husband bought me some expensive organic Ceylon Cinnamon today but I'm only going to take a teaspoon of it in my decaf coffee after dinner if I have something naughty in order to regulate my blood sugar because if I take it daily it might mess with my meds. The rest of the time I am going to eat keto to keep my blood sugar low.
My sister in law tried it and it really didn't do anything for her. I'm going to try it and see what happens. I had some tonight because we had a pot luck yesterday and today I had some leftovers. It was a special celebration for my birthday with my family. Next year maybe I'll try and make more keto friendly things like vegetable lasagne and keto cake?
Figuring out that 20 mg of Lurasidone still has some effect on my blood sugar is hard. I've been on it a year and I'm still not completely like I was before. Anyways, it's a small price to pay for living my life outside of the mental ward. I actually have an amazing body, it's thin but a bit curvy. I just wish my boobs were a bit smaller. I was a B34 and now I'm a B36. I bet going keto 95% of the time will really bring them down.
